Carbohydrate mimics and lectins: a source of new drugs and therapeutic opportunities.
نویسندگان
چکیده
Mimics of oligosaccharides capable of interfering with lectin activity are currently being pursued by a number of groups in an effort to produce tools for glycobiology and to design antagonists of medically relevant lectins. The field is reviewed in this chapter. After a brief overview of the state of the art, examples from our and others' studies on the dendritic cell receptor DC-SIGN are illustrated.
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ورودعنوان ژورنال:
- Mini reviews in medicinal chemistry
دوره 12 14 شماره
صفحات -
تاریخ انتشار 2012